
Regenerative Medicine Denver: Non-Surgical Stem Cell & PRP Therapy
BACK PAIN, KNEES, SHOULDERS, HIPS AND OTHER JOINTS, LIGAMENTS, TENDONS & CARTILAGE.
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Keep Your “Season Pass” Lifestyle. Advanced Regenerative Medicine for Denver’s Active Adults.
You don’t have to choose between a total joint replacement and living in pain. Discover the non-surgical protocols keeping Denverites on the slopes, the trails, and the bike paths—without surrendering a full season to surgery and rehab.
Locally Owned & Operated in Governor’s Park | Serving Denver Since 2012
455 N Sherman St, Denver, CO 80203
Just three blocks south of the Trader Joe’s at 7th & Logan
THE “SLOPE-TO-SCREEN” WHIPLASH IS REAL
Living in Denver comes with a unique physical tax. We sit motionless in I-70 traffic for two hours, then immediately jump out at Loveland Pass or A-Basin to shred Black Diamonds for six hours. Monday morning, we’re back at the desk.
That rapid transition from complete immobilization to high-impact torque creates shear stress on your joints and connective tissue that standard physical therapy often misses. Your body doesn’t get the gradual warm-up it needs—and over time, the micro-trauma accumulates.
You might be facing:
The “Treatment Gap”: You’ve been told you have arthritis, but you’re “too young” for a knee replacement. Your orthopedist says “come back in five years,” but you don’t have five years to wait.
The “Cortisone Cycle”: You’re tired of steroid shots that mask the pain for three months but weaken your tissue over time. Each injection buys you a temporary reprieve, but you can feel the underlying problem getting worse.
The “Altitude Identity Crisis”: You’re watching your friends tackle the Manitou Incline or plan backcountry trips to Breckenridge while you sit on the sidelines. The activities that define your life in Colorado are slipping away.
Does Your Knee Predict the Snow Better Than the Weatherman?
It’s not in your head. It’s barometric pressure pain. In Denver, massive pressure swings before a storm cause the tissues inside your joint capsule to expand, pressing on sensitized nerves. If you can feel the weather changing in your joints, it’s a sign of underlying inflammation—and that’s exactly what we treat.
Healing is Harder at 5,280 Feet. We Give Your Body the Boost It Needs.
In our high-desert climate, two factors work against your natural recovery:
Hypoxic Healing: With 17% less oxygen than at sea level, your body has to work harder to repair soft tissue. The cellular processes that rebuild cartilage and tendon require oxygen as fuel—and at altitude, that fuel is scarce. Research published in the Journal of Applied Physiology confirms that tissue repair mechanisms are measurably slower in hypoxic environments.
Synovial Drought: Denver’s dry air (average humidity often below 30%) contributes to chronic dehydration. This reduces the production of synovial fluid—the “oil” that keeps your joints gliding smoothly. When that fluid thickens or decreases, friction increases, accelerating cartilage breakdown.
At Denver Regenerative Medicine, we bridge that gap using high-concentration biologic protocols designed to overcome the challenges of healing at altitude.

Our Core Modalities: Precision Biologics for Joint Preservation
1. Platelet-Rich Plasma (PRP)
Best for: Tennis Elbow, Rotator Cuff Tendinopathy, Mild to Moderate Knee Arthritis
We draw your blood and use a centrifuge to concentrate the healing platelets—often 5-10 times above baseline levels. This isn’t just a “booster shot.” It’s a construction crew for your damaged tissue.
Platelets release growth factors that signal your body to repair the micro-trauma caused by rocky Colorado trails, repetitive ski moguls, or the impact stress of trail running. Clinical studies in the American Journal of Sports Medicine have demonstrated PRP’s efficacy in reducing pain and improving function in knee osteoarthritis, with effects lasting 6-12 months or longer.
We use image-guided ultrasound to ensure the PRP is placed precisely at the site of tendon degeneration or cartilage thinning—not just “somewhere in the joint.”
Learn more about our Platelet-Rich Plasma therapy protocols →
2. Bone Marrow Aspirate Concentrate (BMAC)
Best for: “Bone-on-Bone” Osteoarthritis, Labral Tears, Major Ligament Injuries
For more severe degeneration, we harvest your body’s own mesenchymal signaling cells from bone marrow. These cells are powerful modulators of inflammation. They don’t “regrow” cartilage like a magic eraser, but they do calm the harsh, catabolic environment inside an arthritic knee.
The result: reduced pain, improved mobility, and—most importantly—preserved joint function. Many patients who were told they needed a total knee replacement have delayed or avoided surgery entirely after Bone Marrow Aspirate Concentrate treatment.
The procedure is performed in-office under local anesthesia. We use fluoroscopy (live X-ray guidance) to harvest marrow from the iliac crest (hip bone) and then concentrate the cells before injecting them into the damaged joint under ultrasound guidance.
3. Image-Guided Precision: The “Blind Injection” Era is Over
Whether we’re treating your hip joint, rotator cuff, or knee, we use High-Resolution Ultrasound or Fluoroscopy for every procedure. We don’t guess. We see exactly where the damage is, and we place the biologics with millimeter-level accuracy.
This matters because a biologic injected into the wrong tissue plane—say, into the fat pad instead of the cartilage interface—won’t deliver results. Precision is the difference between a successful outcome and a wasted procedure.
Why Denver Trusts Dr. Joel Cherdack & The Team
In a market flooded with national franchises and pop-up “stem cell” clinics, stability and reputation matter.
A Denver Legacy (Since 2012): We aren’t a franchise testing a new market. We’ve been a staple of the Capitol Hill and Governor’s Park medical community for over a decade. We’ve treated thousands of Denver patients—many of whom return year after year for maintenance treatments to keep them active.
A+ Rated by the BBB: We hold ourselves to the highest ethical standards. No high-pressure sales tactics. No misleading claims about “miracle cures.” Just honest medical advice about what regenerative medicine can—and cannot—do for your specific condition.
Locally Owned: When you visit us, you’re seeing a dedicated local medical team, not buying into a national chain with rotating staff. Dr. Joel Cherdack has built this practice on relationships, not transactions.
Dual-Location Stability: With successful clinics in both Denver and Colorado Springs, we’re the trusted choice for Front Range residents from Fort Collins to Castle Rock.
Centrally Located in Governor’s Park: Easy Access, No Downtown Gridlock
We know you don’t have time to waste navigating downtown Denver traffic or hunting for parking. Our clinic is located at 455 N Sherman St, sitting right in the heart of Governor’s Park—one of Denver’s most accessible neighborhoods.
From the West (6th Ave): We’re just one block south of the 6th Avenue connector. If you’re coming from Hilltop, Cherry Creek, or Lakewood, take 6th Ave east to Sherman and turn left. We’re on your right.
From I-25 (Lincoln/Broadway Exit): Exit at Lincoln or Broadway and head into the quiet Washington Park Neighborhood. We’re just one block east of the Lincoln corridor—easy to reach without fighting downtown congestion.
The Landmarks: Look for the Trader Joe’s at 7th & Logan—we’re just three blocks south. If you glance north from our street, you’ll see the Gold Dome of the Colorado State Capitol rising above the trees.
Parking: Street parking is available on Sherman St and surrounding blocks. We also have a small dedicated lot behind the building.
Service Areas: We Serve the Entire Denver Metro & Front Range
While our clinic is in Governor’s Park, we regularly treat patients from:
- Capitol Hill & Cheesman Park
- Cherry Creek & Washington Park
- Highlands & LoHi
- Stapleton (Central Park)
- Lakewood & Littleton
- Aurora & Centennial
- Boulder & Fort Collins
- Colorado Springs (second location)
If you’re anywhere along the Front Range corridor, we’re an easy drive via I-25 or I-70.
Frequently Asked Questions about Regenerative Medicine in Denver
Is this covered by insurance in Colorado?
Most regenerative procedures (PRP and BMAC) are not yet covered by major insurance carriers like Anthem Blue Cross, UnitedHealthcare, or Cigna. The treatments are considered “investigational” by many insurers, despite growing clinical evidence.
However, we offer transparent pricing and flexible financing options. Many patients find the total cost is significantly less than the deductible + co-insurance + lost wages associated with major surgery like a total knee replacement.
We provide detailed superbills that you can submit to your HSA or FSA for reimbursement.
Will the altitude affect my recovery after the procedure?
Healing at altitude can be slower due to reduced oxygen availability. However, our protocols are specifically designed to concentrate healing factors to overcome this challenge.
We also provide detailed post-procedure guidance:
- Hydration protocols (targeting 80-100oz of water daily in the first week)
- Supplemental oxygen recommendations for the first 48 hours (if needed)
- Modified activity guidelines to prevent re-injury during the healing window
The goal is to give your cells the fuel and environment they need to maximize the biologic response.
Can I ski or hike immediately after the injection?
We typically recommend a short period of “relative rest” (3-7 days) to let the biologics settle and begin their work. You can walk and perform light daily activities, but we ask you to avoid high-impact or rotational stress during the initial inflammatory phase.
However, unlike surgery—which might take you out for an entire season—our goal is to get you back on the Cherry Creek Trail, the Incline, or the slopes within weeks, not months. Most patients return to full activity within 4-8 weeks, with continued improvement over the following 3-6 months.
How do I know if I’m a candidate?
The best candidates for regenerative medicine are patients with:
- Mild to moderate osteoarthritis (not yet “bone-on-bone,” though BMAC can help even in advanced cases)
- Tendon injuries (rotator cuff, Achilles, patellar tendon)
- Ligament sprains or partial tears
- Labral tears in the hip or shoulder
- Chronic pain that hasn’t responded to physical therapy or cortisone injections
We do not recommend regenerative therapy for:
- Acute fractures
- Active infections
- Severe osteoporosis
- Certain autoimmune conditions
The only way to know for sure is to schedule a Candidate Assessment. We’ll review your imaging (X-rays, MRI), perform a physical exam, and give you an honest recommendation—even if that means referring you elsewhere.
Don’t Let Pain Decide Your Weekend Plans
You live in Denver for a reason. The mountains. The trails. The 300 days of sunshine. Don’t let an injury turn you into a spectator in your own life.
If you’re tired of the “wait and see” approach—tired of cortisone shots that only mask the problem—let’s find out if you’re a candidate for regenerative therapy.
Schedule Your Candidate Assessment Now
Or call us directly: (720) 583-1648
Denver Regenerative Medicine
455 N Sherman St
Denver, CO 80203
Hours:
Tuesday, Wednesday, Thursday: 9:00 AM – 5:00 PM
Monday, Friday: 10:00 AM – 5:00 PM
Saturday: 10:00 AM – 3:00 PM
Sunday: Closed

LETTER FROM THE FOUNDER
Thank you for your interest in learning more about regenerative medicine and the revolution of stem cell therapy. Denver Regenerative Medicine began with a philosophy, a philosophy of staying true to the idea that the practice of medicine should first and foremost, do no harm. Today, advances in regenerative medicine allow us to take a person’s own stem cells, isolate them, concentrate them, and apply them directly to a damaged area of the body. Once there, those stem cells begin to create healthy, new tissue that is comprised completely of your own body’s material! No longer do patients have to undergo barbaric orthopedic surgeries and weeks of painful physical rehabilitation. In my view, this represents a paradigm shift in how medicine treats arthritis and injuries to the musculoskeletal system. Instead of drugs, surgeries, and artificial parts, we can now use the body’s own regenerative and restorative components and focus them on an injured area. The beauty of stem cell therapy is in its simplicity. It is my hope and expectation that we will be able to help thousands to avoid painful and unnecessary surgeries, as we remain on the forefront of the advancements in regenerative medicine.
Sincerely,
Dr. Joel Cherdack



